BDBM50398716 CHEMBL2179618::US10227295, Compound 5g::US9409858, 5g::US9751832, Compound 5g::US9956192, Compound 5g

SMILES CCCCN(Cc1ccc(cc1)C(=O)NO)C(=O)Nc1ccccc1

InChI Key InChIKey=JZWXMCPARMXZQV-UHFFFAOYSA-N

Data  4 KI  75 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50398716   

TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50398716(CHEMBL2179618 | US10227295, Compound 5g | US940985...)
Affinity DataIC50:  6.68E+3nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50398716(CHEMBL2179618 | US10227295, Compound 5g | US940985...)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of human HDAC3 expressed in HEK293/T17 cells pre-incubated for 10 mins before Ac-GAK(Ac)-AM substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50398716(CHEMBL2179618 | US10227295, Compound 5g | US940985...)
Affinity DataIC50:  6.68E+3nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50398716(CHEMBL2179618 | US10227295, Compound 5g | US940985...)
Affinity DataIC50:  6.08E+3nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50398716(CHEMBL2179618 | US10227295, Compound 5g | US940985...)
Affinity DataIC50:  238nMAssay Description:Inhibition of full length human recombinant HDAC3 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In DepthDetails PubMed